Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. Anthonia OC, Ikechukwu UR, Uzoma NO, Sunday ELU. Anal Biochem. A., Bezerra, G. A., Matos, F. J., and Viana, G. S. Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. Total reaction mixture of 3ml contained 2.95ml of 0.05M sodium carbonate buffer (pH10.2), 0.02ml tissue sample and 0.03ml of epinephrine (2mM) in 0.005N HCl was used to initiate the reaction. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. The mixture was incubated at 28C for 30min and the absorbance read at 550nm against the reagent blank. These tropical plants are not very fussy about soil. The antidiabetic effect of justicia is through the inhibition of-amylase and -glucosidase, the carbohydrate metabolizing enzymes, and also through its hypolipidemic potential. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. Total protein concentration in tissue homogenates were determined using biuret method Tietz [16]. Justicia carnea and Cnidoscolus aconitifolius were tested for their capacity to ameliorate the fecundity of chloramphenicol-induced lymphoma in rats. 2. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. Rats in the 3 different groups received 10, 100 and 1000mg/kg body weight of JCEE orally using oral gavage. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. However, the mechanism by which phytochemicals act as prooxidants in-vivo is still under investigation [25]. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. what are the pros and cons of testosterone replacement therapy? J Ethnopharmacol. https://doi.org/10.13040/IJPSR.0975-8232. Provided by the Springer Nature SharedIt content-sharing initiative. 3. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. In phase I, rats were randomized into 3 groups of 3 rats per group. Too much sun can scorch the leaves, and too little will result in fewer flowers. 2012;9(1):817 https://doi.org/10.4314/ajtcam.v9i1.12. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). if you add justicia carnea leaves in avocado seed tea, you may just get yourself the best remedy for cardiovascular diseases. Names of Justicia Betonica in various languages of the world are also given. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. The acute toxicity test also proved that justicia carnea leaves are safe for consumption. The unique flower clusters and bright coloring has made it a popular choice among landscape artists and amateur gardeners as well. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. https://doi.org/10.3390/molecules191221442. In phase two, three rats were separated into 3 groups of one rat per group. Ethanol extracts of J. carnea leaf increased RBC, hemoglobin and platelet with significant increase (p<0.05) in groups that received higher dose (>500mg/kg b.w) of extract compared to the control. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Absorbance reading was taken at 620nm regularly at an interval of 1min against reagent blank. Despite the use of Justicia carnea and other reported scientific studies, there are no reports on its effects on the major organs of the body. hindawi publishing corporation evidence-based complementary and alternative medicine. Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. 1.3.1 Aetiologyof Anaemia Anaemia may be due to a single factor such as a nutritional deficiency or multifactorial (McEvoy, 2013). Emmanuel Sina Akintimehin. Ewe eje isnt capable of causing any side or negative effects if consumed moderately. It has been shown also that other specie of justicia improve central nervous system functions and health and protect it from toxic damages. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. Ogwu obara can act as a blood tonic for women during menstruation. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). Rats that received 50 and 100mg/kg body weight JCEE showed significant (p<0.05) increase in liver weight while other doses showed no significant difference compared to the control. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. long (20 cm), densely packed with pink to crimson tubular flowers. Pinch Justicia carnea plants back after theyve flowered. Control treatment showed normal central venules without congestion, the morphology of the hepatocytes appear normal, the sinusoids appear normal with no observable form of infiltration and no observable pathological lesion seen. The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. 2013;1:38898. You can add the leaves and water altogether in a pot and allow to boil till the water turns red. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. While the renal tubules across the tested groups were normal with the interstitial spaces showing moderate congestion and hemorrhage, there appeared some abnormalities in the renal cortex (such as few sclerotic glomeruli with moderately dilated capsular spaces) resulting in fair architectural structure of the kidney (Fig. Haematoxic effects following ingestion of Nigerian crude oil and crude oil polluted shellfish by rats. View abstract. It has already been pointed out that this plant is used traditionally to boost blood production among the people of southern Nigeria. 400). The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). Cookies policy. statement and This encourages better flowering and bushier and denser new growth. This is why you should avoid potting them if you live in colder areas. Filed in Biochemistry Project Topics, Current Projects by TMLT Editorials on September 22, 2020. The Pros and Cons of Creatine You Should Know. Ewe eje is mainly given to persons who want a blood boost such as pregnant women, persons suffering from anemia and other convalescents. However, scientifically it is called Justicia carnea. In recent time, copious attention has been focused on the use of medicinal plants in the management and treatment of ailments such as anemia, diabetes and malaria. For a few weeks, the cutting should be watered every day to promote root development. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. This post was last modified on January 2, 2023 5:23 pm. The Pharmacobiochemical Effects of Ethanol Extract of Justicia secunda One of the health benefits of justicia carnea is in boosting immune system. Nutritive properties of aqueous extract Justicia carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male wistar albino rats. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. Tropical habitats mean constant moisture. In these groups, from mild to severe order; the renal cortex appears distorted, Renal glomeruli and dillated capsular spaces appeared collapsed with characteristic pyknosis of the mesangial cells, The renal tubules, interstitial spaces, appears distorted with presence of red inflammatory cells, hemorrhagic cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane (red arrows). However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. International Journal of Biochemistry Research & Review. When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. Related: The Persian Shield plant is also in the Acanthaceae family. Braz. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . JUSTICIA PECTORALIS - Uses, Side Effects, and More - WebMD They are also needed in strong bone formation, and in cellular and neuronal functions. The leaves are rich in carbohydrates and proteins, which are for energy production and maintenance of cellular activities. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. View abstract. Mukinda JT, Syce JA. It helps in replenishing blood lost during period. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Sun M, Zigma S. An improved spectrophotometer assay of superoxide dismutase based on epinephrine autoxidation. The compound responsible for this activity is lignan. 2. Phytochemical profile, antioxidant, -amylase inhibition, binding Justicia pectoralis might have many different effects in the body. The aim of this study is to evaluate the effects of J. carnea leaf extract on hematology indices and organ antioxidant system in healthy wistar rats. Different drugs are used but many depend mainly on plants and herbal products for its treatment. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. Effect of methanol leaf extract of Justicia carnea on serum albumin (ALB) and total protein (TP) concentration CCl 4 intoxicated rats. There are several nutritional benefits of justicia carnea leaves. Philadelphia: WB. One of the symptoms of diabetes is elevated blood glucose level. 2010;32(1):1328 https://doi.org/10.3109/08860220903367585. Tietz NW. 2003;66:1499503. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. It may also affect the activity of hormones. The concentration of reduced glutathione content of the tissues was estimated according to Sedlak and Lindsay [19] method. Cut back after flowering to 2-3 nodes from the ground to keep the plant bushy and promote new blooms. Nigeria's medicinal plant: Justicia carne (Ewe eje) - PressReader Keep in mind that natural products are not always necessarily safe and dosages can be important. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. In this study, the aqueous leaf extract of Justicia carnea was used. Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Justicia carnea (Brazilian Plume) - Gardenia.net In-vitro Antioxidant Screening of Ethanol Extracts of Costus afer and View abstract. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. PDF Effects of Ethanol Leaf Extract of Justicia Carnea on Biochemical Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. Antianaemic potentials of some plant extracts on phenyl hydrazineinduced anemia in rabbits. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Onoagbe IO, Attah V, Luther MM, Esekheigbe A. Hypoglycemic and anti-diabetic effects of Morinda lucida and Tetracera alnifora in normal and streptozotocin-induced diabetic rats. These antibodies help prevent infections and fight off diseases. (2020). PubMed Central California Privacy Statement, 4. Part shade is the ideal growing condition for Brazilian plumes. 2008;79:3326 https://doi.org/10.1016/j.fitote.2008.02.005. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. You can add milk or honey for taste before drinking. Google Scholar. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. These animals were obtained from the animal house of the Department of Chemical Sciences, Ladoke Akintola University of Technology Ogbomoso Oyo State, Nigeria. Prepare the existing soil by breaking it up with a spade or hoe. It can be used to manage diabetes consition properly. Afr J Tradit Complement Altern Med. This special leaf can be found around us- in our neighborhood. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Organic extract of Justicia pectoralis Jacq. The kidney of rats treated with doses of J. carnea ethanol extract revealed dose dependent degree of renal injury (Fig. One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. Antioxidants & redox signaling Forum Review. Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. 2005 - 2023 WebMD LLC, an Internet Brands company. Why urban citizens in developing countries use traditional medicines: the case of suriname. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Plantcaretoday.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com, how to get rid of leaf eating caterpillar. Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. We use cookies on this website, you can read about them here. J. Pharmacogn. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. The Justicia carnea leaves are rich in B-vitamins. This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. This is not a big concern as it wont kill the plant and you will find a solution at your local gardening center. Macrocytic and hypochromic anemia usually results due to increased mean corpuscular volume (MCV) and decrease in mean corpuscular hemoglobin concentration [30]. PubMed 1978;52:30210. It is a creeping, perennial plant and grows up to 2 meters tall. Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. The spread is equally glorious and can take up 12 15 inches of space. The resultant liquid would turn crimson red. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. However, caution should be taken as higher dose at 1200mg/kg could cause noticeable tissue injury. Justicia carnea has been used in traditional medicine to treat diabetes. Stover PJ, Caudill MA. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. It also increases good cholesterol levels. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. J Ethnopharmacol. The unique and beautiful tubular flowers of Justicia carnea highlight the plant. Too much fertilizer is damaging for your plant. PubMed 8-10 Justicia carnea leaves. Radhika J, Sathya S, Jothi G, Japasheba JL. 10.9734/ijbcrr/2020/v29i630194. Phytochemical profile, antioxidant, -amylase inhibition, binding Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. Another health benefit of ewe eje leaves is in cardiac protection and hypolipidemic effect. 2019;30(4):64554. Side effects of Ewe eje (Justicia carnea leaf Side Effects). 2023 BioMed Central Ltd unless otherwise stated. Sedlak J, Lindsay RH. Molecules (Basel, Switzerland), 19(12), 2144221461. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America.The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. Estimation of total, protein-bound, and non-protein sulfhydryl groups in tissues with Ellmans reagent. Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes. https://doi.org/10.35841/biomedicalresearch.30-18-666. Materials and Methods It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013). Faiza R, Waqas KK, Adeel M, Muhammad G. Detection of bioactive fractions of Justicia adhatoda leaves. Biomed Res. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. Maturitas 2010;66(3):315-322. 2008;108(9):14807. Nutritive properties of aqueous extract Justicia carnea leaves and its Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. Google Scholar. 32 years old (Greco et al., 1974), long-term treatment side effects are becoming more critical. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . Canadian J Appl Sci. 2007;39(1):4484. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. Cookies, This site is protected by reCAPTCHA and the Google, Justicia scheidweileri (Purple Shrimp Plant), Justicia americana (American Water-Willow), Want Garden Inspiration? Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves Cardioprotective role of Justicia traquebareinsis Linn. Anal Biochem. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. 200, 500 and 1000 mg/kg bw of Justicia carnea showed a significant (p<0.05) decrease in the activities of ALT, AST and ALP, and bilirubin level while total protein and albumin levels increased significantly (p<0.05) when compared with the rats treated with CCl alone. WebMD does not provide medical advice, diagnosis or treatment. 7 Potential Health Benefits Of Justicia Carnea (Ewe Eje) In its native habitat, the Justicia carnea plant grows upright and may reach 3 5 feet tall. 1983;53:27589. List of various diseases cured by Justicia Betonica. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. The hematopoietic systems represent a sensitive target of toxic compounds and an essential index of physiological and pathological status in experimental animals [24]. These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. 15 Amazing benefits of brocoli juice and side effects. Chanda S, Parekh J, Vaghasiya Y, Dave R, Baravalia Y, Nair R. Medicinal plants - from traditional use to toxicity assessment: a review. In a pot, pour in a cup of water and bring to a boil. Studies have shown that ewe eje isnt capable of causing damage to the liver. Inter J Pharm Sci Res. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Where, A=absorbance, TV=total volume, SV=sample volume, =extinction coefficient, TP=total protein. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. Ewe eje or ewe ajeri is prepared differently by different folks. Growing up, we were told many biblical stories, Negro pepper (Xylopia aethiopica) is a spice plant that possess several health benefits, which make it an indispensable, Eating for its sour taste when fairly ripen and sweet taste when well ripen, star apple finds favor, Fertility tree (Newbouldia laevis), also known as boundary tree, Ogirisi in Igbo, Adikuru in Hausa and Ewe akoko, Guava (Psidium guajava) is a well known tropical tree which is widely grown for its fruits. long (20 cm), densely packed with pink to crimson tubular flowers. Beijing: Chemical Press; 2011. Fitoterapia. Lorke D. A new approach to practical acute toxicity testing. Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . Anal Biochem. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). 2017;16(2):21730 https://doi.org/10.17306/J.AFS.2017.0492. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. The absorbance was read at 412nm against the reagent blank. W Afr J Biol Sci. volume7, Articlenumber:2 (2021) After 72h of soaking, the wine (dark purplish red) colored filtrate was filtered using a double cheese cloth, concentrated under reduced pressure using rotary evaporator and subsequently water bath at 40C to obtain a slurry (dark purple) extract termed Justicia carnea ethanol extract (JCEE). Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants).
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