Super Bowl champs ready for the draft . -- Jake Trotter, Bold prediction: The Chargers have yet to put together a 100-rushing yard performance this season, but that will change Sunday against the Browns. He is the first player with nine sacks through the first four games of a season since Kabeer Gbaja-Biamila recorded nine in 2001. -- Jeff Legwold. Dolphins 19, Titans 17 -- Cameron Wolfe, The Dolphins allowed 235 rushing yards in last year's loss to the Titans. Read more. They haven't lost three straight road games since 2018. Why Lions GM is getting high praise See Week 5 rankings. In that case, at home, Stafford has the edge. Spread: GB -8.0 (41), What to watch for: This could be a nightmare matchup for the Packers' defense. Cowboys 27, Packers 23 -- Rob Demovsky, For the second consecutive week, the Cowboys are facing a team with a 10-day break. The Eagles' pass defense is vulnerable, but Luke Falk -- a dink-and-dunk passer -- doesn't have enough arm to exploit the matchup. -- Nick Wagoner. The Cowboys will want to prove last week was more of a fluke than a trend. Betting nugget: Baltimore is 12-2-2 ATS when the line is between +3 and -3 since 2019 (Lamar Jackson's first full season as starter). Click on each game for the game preview and CFN Prediction Week 5 NFL Expert Picks Read more. See Week 5 rankings. NFL Expert Picks - Super Bowl Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 Week 18 Wild Card Divisional Round Conference Championship Super Bowl hidden The Bills' offense -- which has gone three-and-out on 48 percent of drives this season, second most in the NFL -- will be playing short-handed at wide receiver because of a thumb injury to No. To take advantage of the Ravens' weak spot, the Steelers could push Rudolph to unleash more deep throws. -- Josh Weinfuss, Bold prediction: Arizona will double its sack total on the season and take Jalen Hurts down four times. Our NFL Nation reporters bring us the biggest keys to every game and a bold prediction for each matchup. Theres not a whole lot of tape out there on Trubisky, which is a disadvantage for Minnesota in game planning. So, these teams could have to rely on their defenses. Cardinals 30, Eagles 27 -- Tim McManus, It's hard to know what the Jaguars are going to get from QB Blake Bortles each week, and this week may be even more of a mystery because the Jaguars may be without WR Marqise Lee because of a rib injury. Walder's pick: Chargers 24, Browns 20 Neal has played well in the past while filling in for Jamal Adams and appears to be in line to get another opportunity, having replaced Jones in the fourth quarter of Seattle's win over Detroit. Cimini's pick: Eagles 27, Jets 9 What to know for fantasy: With two games of seven-plus targets already this season, plus a TD reception in Week 4, Bengals tight end Hayden Hurst has potential. Read more. Top Week 5 NFL predictions One of the model's strongest Week 5 NFL picks is that the Titans (-2.5) cover against the Commanders in almost 60% of simulations. Stat to know: Tampa Bay's Shaquil Barrett leads the NFL with 9.0 sacks through four games. Without Tyreek Hill, Chiefs' receiving load shifting to tight ends and backs Patrick Mahomes says Andy Reid 'stole the show' in TV ad, 9:30 a.m. 1-ranked run defense to power the Browns to their second win on Monday Night Football this season. Bengals 14, Bills 10 -- Katherine Terrell, Coach Todd Bowles says "2-2 is nothing to brag about." Additionally, the Eagles are averaging a league-high 8.79 passing yards per play while the Cardinals are giving up 7.36, which ranks 25th in the league. What to know for fantasy: Zach Ertz finished last season as TE2 despite not scoring his first touchdown until Week 5. The 2023 NFL Draft continues today in Kansas City! See Week 5 rankings. Among those players, no one is averaging fewer fantasy points per touch than Sony Michel (0.44). -- Brady Henderson. -- Todd Archer, Bold prediction: The first team to 30 rushing attempts will win. Betting nugget: Since the start of last season, Dallas is 9-1 ATS on the road and 13-2 ATS in conference games. Matchup rating: 65.6 | Spread: NO -3 (46.5), What to watch for: Is this the week we see the training wheels come off for Teddy Bridgewater? NFL: Mahomes favorite for game's MVP 198 days ago NFL Week 4 of the 2022-23 NFL season has come to a close. Betting nugget: Both times Rodgers faced the Cowboys in Dallas, Green Bay won the game outright as an underdog (2016 divisional round and 2017 Week 5). 1, Panthers' Bryce Young is all 'business now', Top picks Christian Gonzalez, Keion White reflect Patriots' ideal identity, Big takeaways from the NFL draft: A historic QB class, the rebuilt AFC South and new GMs thriving, NFL Nation sizes up all 259 draft selections, XFL semifinals: Defenders roll Sea Dragons, set up title showdown with Renegades. Getting back to what they do best -- stopping the run -- is paramount this week. He is tied with Russell Wilson for the most in the NFL in that span. 1 overall pick, are hours away from being on the clock -- which means the 2023 NFL draft has arrived. The Colts, meanwhile, are scoring on 40% of their possessions, 11th best. The Bills aren't known for a traditional ground game, but the Steelers' defense is giving up an average of 131.5 rushing yards per game. They're catching the Eagles' normally dominant offense at the right time, with left tackle Jordan Mailata (shoulder) and right guard Isaac Seumalo (ankle) dealing with injuries. This has the makings of another close loss. Stat to know: The Dolphins' 11-2 record since 2021 Week 9 is tied with the Chiefs for best in the NFL. 3 all-time rusher Barry Sanders, 1 p.m. Washington's pass defense is allowing 259.8 yards per game, but 294 yards per game at home. The first round of the 2023 NFL Draft certainly had its moments, as three quarterbacks went within the first four picks and each of the major conferences had a player selected for the first time . Tannehill had only two 300-yard passing games last season and has yet to have one this year. 1, Panthers' Bryce Young is all 'business now', Top picks Christian Gonzalez, Keion White reflect Patriots' ideal identity, Big takeaways from the NFL draft: A historic QB class, the rebuilt AFC South and new GMs thriving, NFL Nation sizes up all 259 draft selections, XFL semifinals: Defenders roll Sea Dragons, set up title showdown with Renegades. FPI prediction: SF, 72.5% (by an average of 8.3 points), Matchup must-reads: Chubb's running finally launches Browns' offense How good are first-place 49ers? Chicago knows how dangerous Minnesota's run game can be, so they'll stack the box to try to take away Dalvin Cook and make Cousins beat them with his arm. Arizona has given up 17 sacks while the Eagles have 10 on the season, but Palmer called the Eagles' front seven one of the best he will face this year. Walder's pick: Jaguars 31, Texans 9 See Week 5 rankings. The Cowboys will be the third pass defense the Rams have faced so far ranked in the top seven, and their varied pass rush will make life difficult for Stafford. Since Alex Smith got injured in Week 11 of last season, it has had an NFL-high five starting QBs. They have an NFL-best plus-eight turnover margin. NFL expert picks, predictions, lines for Week 5 highlighted by the Giants at Green Bay, Dallas at the Rams, and Las Vegas at Kansas City NFL Expert Picks, Predictions: Week 5 * next to the pick means the team will win, but not cover. Here are some lines that could change after this week's slate concludes. What to know for fantasy: Derek Carr has completed over 70% of his passes in four straight games against the Chiefs and cleared 18 fantasy points in three of those contests. -- John Keim, Bold prediction: New England running back James White will score two touchdowns, with his playing time rising because he's a top pass protector and the Redskins are a heavy blitz team. -- Jamison Hensley, Bold prediction: Ja'Marr Chase will have more than 125 receiving yards. While they are struggling in the passing game, the Bears are third in the NFL in rushing yards (709). Read more. play. Read more. Moody's pick: Cowboys 23, Rams 20 Panthers QB Young all 'business now', Bold prediction: Bears rookie running back David Montgomery finally breaks through with 100 rushing yards. UPDATE: I made seven changes to my final mock draft -- starting with the No. -- Mike Reiss. What to know for fantasy: Murray leads the NFL with 187 opportunities this season (pass-plus-rush attempts). Herbert also totaled five touchdowns. See Week 5 rankings. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. All newly updated picks . -- Courtney Cronin. Stat to know: The Titans rank 28th in the NFL in both sacks allowed (17) and pressure rate (34.0%). He needs nine receptions on Sunday to break the five-game record, held by Zach Ertz (2018) and Eric Johnson (2004). Since the start of last season, 13 of the Bills' 20 games have gone under. That's not the attitude a winless team needs. Betting nugget: The past four times Jacksonville was a favorite, it lost the game outright, with three of those losses coming against Houston. Vikings 20, Bears 17 -- Courtney Cronin, The Bears are 14-2 in their past 16 home games against the Vikings dating back to the 2001 season. It sounds crazy, but the Jets will win their third straight game. The role is great, but don't forget DeAndre Hopkins' suspension has just two weeks left on it. -- Jake Trotter. But he also has not been held under 50 receiving yards in back-to-back appearances since Weeks 11 and 13 in 2017 (he did not play in Week 12). ET | Fox NFL Power Rankings Week 5 bet now, bet later Week 5 spot bets Under 50.5 (-110) Combined, both teams have begun the season 3-5 O/U while the Bengals are riding a three-game Under. Washington opened the. Read more. ET | NFL Network The Cardinals have allowed a league-high 20 sacks; the Bengals are right behind them at 19. They'll be energized, while at home against a tough division rival, and will sneak out another close win. Betting nugget: Mahomes is 7-1 outright and 6-2 ATS against Las Vegas. Swift likely out again vs. Patriots, source says, What to watch for: The Vikings' defense has given up 1,054 passing yards this season, seventh-most in the NFL, as it meanders through the adjustment process to coordinator Ed Donatell's 3-4 scheme. What to know for fantasy: Jameis Winston has thrown three-plus touchdown passes in consecutive games for the first time in his career, but now he gets a Saints team against which he has never thrown three-plus touchdown passes in a game. Colts 21, 49ers 17 -- Mike Wells, Marcus Mariota's playing status could be unknown until Sunday, but the Titans have problems to solve even if he does find a way to play. 2020 NFL draft order: Top 20 picks Read more. It's all here to help get you ready for a loaded weekend of NFL football. Herm Edwards and Tedy Bruschi discuss the outcome of what could be a high-scoring game in Dallas. Read more. Tyrod Taylor has excelled in passing to Charles Clay and LeSean McCoy this season, but the Bengals boast the NFL's lowest yards per catch (6.49) by opposing tight ends and running backs. Rams 24, Seahawks 23 -- Brady Henderson, The Rams are feeling really good about themselves, coming off a big road win against the Cowboys. Steelers' first draft by Khan 'aggressive' Finally, Seth Walder and Eric Moody give us final score picks for every game. Teicher's pick: Chiefs 35, Colts 27 More: NFL Week 5 odds: Money lines, point spreads, over/under for every Week 5 NFL game. Betting nugget: The Broncos are 1-7 ATS in their past eight games. -- Adam Teicher, To celebrate 100 years of pro football, Peyton Manning travels the country to see the people and places that made the NFL the NFL. Watch on ESPN+ More , Bold prediction: Nope. Los Angeles Chargers at New Orleans Saints. Our NFL Nation reporters bring us the keys to every game, a bold prediction for each matchup and final score predictions. -- Rob Demovsky, Bold prediction: Aaron Rodgers throws for 300-plus yards and at least three touchdowns. The Lions' defense gets another interception and Stafford throws for three touchdowns. Wagoner's pick: 49ers 27, Browns 24 Injuries: Eagles | Steelers. As Giants defensive coordinator Wink Martindale said of the Packers QB, 'It's like owning a python and saying, 'Don't worry about it, he won't bite.'" -- David Newton, Bold prediction: San Francisco 49ers defensive end Nick Bosa will have three sacks in his second career game against the Panthers. And the Dolphins' struggling offense presents three receivers who could give them fits once again.